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Evaluation of tuberculosis diagnostic criteria in children


S. Khalilzadeh, M. Hassanzad*, N. Baghaiee, M. R. Bloorsaz and A. A. Velayati
Pediatric Respiratory Disease Research Centre, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

The research was performed to review the diagnostic criteria for tuberculosis (TB) in 198 children with confirmed TB. A cross-sectional descriptive study was conducted on a series of 525 children aged 1 to 15 years. Among 525 patients, 198 were diagnosed with TB. Data were collected from patient records, chest radiographs, and laboratory examinations. Demographic and diagnostic characteristics of patients were reviewed using the currently available criteria. In this study, 38.9% of patients were male and 61.1% were female. Among all patients, 34.8% were Iranian and 65.2% were Afghanis. In total, 82.8% of patients reported close contact with a TB case. Among all patients, 13.1% had extrapulmonary tuberculosis, 72.7% had pulmonary tuberculosis, and 14.1% had both pulmonary and extra pulmonary involvement. The frequency of Tuberculin Skin Test (TST), contact, clinical symptoms, radiograph findings, and bacteriology as diagnostic methods was 79.3, 83.8, 83.8, 85.9, and 58.1%, respectively. In our case, 90.4% of patients fulfilled the criteria. A high diagnostic value was determined for smear and culture of gastric aspirates in children. However, this could not be considered as a gold standard for diagnosis of tuberculosis in children. The results of our current diagnostic criteria showed a significant efficacy and accuracy of the mentioned criteria
Key words: Child, tuberculosis, diagnosis

Download ZIP Download PDF African Journal of Microbiology Research Vol. 6(26), pp. 5440-5444, 12 July, 2012

 

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مرکز درمانی سل و بیماریهای ریوی مسیح دانشوری

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Pediatric Respiratory Disease Research Center

 

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