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Chest CT Manifestations in Children with CVID: A 10-Year Report

Mohammad Reza Boloursaz 1, Soheila Khalilzadeh 1, Pegah Rahmati nezhad 1, Mehrdad Bakhshayesh Karam 1, Alireza Mahdaviani 1, Leila Mosadegh 1, Maryam Hassanzad 1, Seyed Mohsen Mir Hosseini 2
 1Pediatric Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, 2Chronic Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran


Background: This study aimed at evaluating HRCT pulmonary manifestations in children with Common Variable Immunodeficiency (CVID) hospitalized in the Pediatric Ward of Masih Daneshvari Hospital during a 10-year period. Materials and Methods: This retrospective study evaluated 25 children hospitalized with the diagnosis of CVID in the Pediatric Ward of Masih Daneshvari Hospital from 2001 to 2011 and their pulmonary HRCT scans were evaluated


Results: The most common pulmonary HRCT findings were lymphadenopathy (66.7%), bronchiectasis (50%), air trapping (33.3%) and peribronchial wall thickening (33.3%). The highest percentage of CT-scan findings was detected in patients aged 13-17 yrs


Conclusion: Most of the pulmonary changes due to CVID are preventable or treatable. Also, it is possible to prevent irreversible complications of disease if it is diagnosed early. Therefore, HRCT is strongly recommended as an accurate and effective method for monitoring and fast recognition of pulmonary manifestations of the disease especially bronchiectasis which is a very common finding indicative of poor prognosis
Key words: Common variable immunodeficiency (CVID), CT scan, HRCT

Download ZIP Download PDF                                                             Tanaffos 2012; 11(4): 56-59

 

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