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Inherited CARD9 deficiency in otherwise healthy children and adults with Candida species–induced meningoencephalitis, colitis, or both

Pediatric Respiratory Disease Research Centre, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Candida species are commensal yeasts colonizing the skin and digestive tracts of most healthy subjects. However, they can cause mucocutaneous candidiasis, which when chronic (ie, chronic mucocutaneous candidiasis [CMC]) is commonly

Interleukin-12 gene polymorphism in children with BCG-osis from Iran

Pediatric Respiratory Disease Research Centre, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
In many developing countries, like Iran, newborns receive the BCG vaccination for prophylaxis against mycobacterial infections. Although in many children or infants BCG infection after BCG vaccination is rare, children with

Nonspecific Interstitial pneumonia (NSIP)/ Overlap or Distinct Entity

Pediatric Respiratory Disease Research Centre, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
In medicine, the term overlap is very common, to the extent that there is even a syndrome with this name. Overlap is also frequently seen in pulmonary fibrosis, such that expert pathologists use diagnoses such as UIP/sarcoidosis or UIP/HP

Qualification Study of Two Genomic DNA Extraction Methods in Different Clinical Samples

Pediatric Respiratory Disease Research Centre, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Genomic DNA is a key component for genomic research. After collection of clinical samples, isolation of gDNA is the first step to run molecular diagnostic assays(1). Thus, it is essential to obtain highly pure gDNA from the sample populations

Quantitative Evaluation of High-Resolution CT Findings in Advanced Cystic Fibrosis Patients Based on the Brody Scoring

Pediatric Respiratory Disease Research Centre, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Cystic Fibrosis (CF) is the most common fatal genetic disorder in white-race communities with a prevalence of 1:2500. Mutation in CFTR gene is its main cause (1-4), yet the reason of this genetic anomaly is unknown (3). Clinical progression

Relationship of Occupational and Non-Occupational Stress with Smoking in Automotive Industry Workers

Pediatric Respiratory Disease Research Centre, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Tobacco use is the second cause of mortality worldwide (1) and the firs cause of preventable morbidity and mortality (2). Cigarette smoking caused more than 100 million deaths in the 20th century. If not intervened, this figure will reach one billion

Silicoproteino-tuberculosis: Three distinct entities or a unique entity: A case report and review of the literature

Pediatric Respiratory Disease Research Centre, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Silicosis occurs in association with mining, quarrying and tunneling. Yet recently, sandblasting with purpose of abrasion and in preparing metal surfaces for painting, cleansing foundry castings and cleaning building exteriors has

 

Sleep-Disordered Breathing as Presenting Manifestation of Chiari Type I Malformation: A Case Report

Pediatric Respiratory Disease Research Centre, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Sleep-disordered breathing consists of apnea and hypopnea, which are repeated breathing pauses and decreased breathing during sleep, respectively. Apneas may be either central or obstructive. Central sleep apnea (CSA) is repeated

 

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